UZH Blockchain Center started its activities in 2017, and was formally established as a Competence Center in 2019. Since then, it has organised a wide range of academic, educational, and industry-related activities. It thus became the largest and most active academic cluster in Switzerland, a World-wide blockchain hub.

The Center is composed of 22 Faculty members from two Faculties and including Informatics, Business, Economics, Finance, Regulation, Law and Complexity Science. It hosts above 40 researchers from the University of Zurich and top-scholars.